Mechanism of tripeptide of gata oona

Tripeptide oona gata

Tulaga fa'avasega, HPLC≥98%

Igoa Igilisi: (2S) -beta-alanyl-l-prolyl-2, 4-Diamino-n -(phenylmethyl)butanamide acetate

Aliases: (2S) -beta-alanyl-l-prolyl 2, 4-diamino-n -(phenylmethyl) butyricoacetate;(2S) -beta-alanyl-l-prolyl-2, 4-Diamino-N -(phenylmethyl)butanamide acetate;SYN-AKE;gata-tripeptide;H – beta – Ala – Pro – Dab – NHBzl.2 acoh;gata tr

Numera CAS: 823202-99-9

fua mole: C19H29N5O3.2(C2H4O2)

mamafa mole: 495.58

Folasaga:

Fa'asologa: H-β-Ala-Pro-Dab-NH-Bzl

Fa'aaliga: Pa'epa'e pa'epa'e

Fa'atomuaga puupuu:

Snake venom peptide ose tama'i peptide e fa'atusaina le gaioiga oona a gata.E le o se gata oona, ae o se polypeptide gaioiga e tutusa ma gata.O peptide oona gata e lima taimi sili atu ona aoga i le faʻaitiitia o laina malosi nai lo le Botox, ma i suʻega vivo na faʻaalia ai ina ua maeʻa le 28 aso o le faʻaaogaina na i ai se aafiaga e faʻaitiitia ai maanuminumi e 52%

Malosiaga:

1. Maanuminumi ma anti-matua

2. Fa'amama le a'afiaga o le pa'u

3. Mea tau tausiga mo mata, ua ma lima

4. Faʻasaʻo le paʻu o le paʻu, faʻamaeʻaina le paʻu, agavaivai ma maaleale, faʻaleleia le tino atoa

5. E mafai ona ulu i totonu o le paʻu loloto o foliga, tausia le paʻu, ma aveese faʻailoga na totoe i tausaga

6. Ta'alo se aafiaga fa'asusu ma fa'asusu, ina ia vaivai ma lamolemole le pa'u, matagofie e pei lava o taimi uma.

7. Faʻasaʻo, faʻafefe le matua, faʻaalia foliga faʻafefe V-foliga, faʻaitiitia le paʻu o foliga talavou

8. Puipui le paʻu mai le gaosiga o le melanin

Aafiaga:

O le dipeptide diaminobutylbenzylamide diacetate/venom-like tripeptide e mafai ona faʻaaogaina e fai ma oloa e faʻaleleia lelei ma faʻamalo le maanuminumi malosi e ala i le faʻamalieina o maso mata.O le gaioiga tripeptide e galue i le auala lava e tasi e pei o Waglerin1, o le neuromuscle-blocking compound i TempleViper venom.O tripeptide pei o gata oona e fa'aoga i le po'o fa'asolo i tua ma e mafai ona fa'afo'i fa'afeagai o le muscular nicotinic acetylcholine receptor (nmAChR).gata gata oona tripeptide fusia nmAChRεsubunit e puipuia ai le tuufaatasiga o le acetylcholine ma le faʻapipiʻi faʻapipiʻi, e mafua ai ona tapunia le faʻapipiʻi faʻapipiʻi, i tulaga tapuni e le mafai ona faʻaogaina le ion sodium, e le mafai ona faʻaleagaina, poloka faʻafefe o le neura, malolo maso.